Structure And Dynamics Of Weakly Interacting Species
Techniques: 2PA and pump-probe
Another area of study examines weak interactions between molecules in solution and seeks to understand how solvent-solute interactions affect the energy and geometry of the interactions. We are also interested in learning more about halogen bonding interactions. These halogen interactions, which typically are intermediate in strength between van der Waals forces and hydrogen-bonds, are important for controlled crystallization of new materials, supramolecular chemistry, and numerous biological systems. We are investigating the dynamics of several different halogen-bonding complexes using two-photon absorption spectroscopy. These electrostatic attractions play a role in molecular recognition and binding, as well as substrate specificity and binding, effects that could potentially be exploited in the manufacturing of new pharmaceuticals.